Histopathologic Alterations in Ovarian Papillary Serous Cystadenocarcinomas After Neoadjuvant Chemotherapy: Possible Clinical Significance
نویسندگان
چکیده
منابع مشابه
Tumour morphology after neoadjuvant chemotherapy as a predictor of survival in serous ovarian cancer: an experience from a tertiary care centre in India.
Serous ovarian cancer is the most common malignant ovarian tumour. Traditional management consists of surgical resection with postoperative chemotherapy. Currently neoadjuvant chemotherapy is offered to patients with advanced stage disease. The present study aims to analyse the histomorphological alterations in serous ovarian cancer following neoadjuvant chemotherapy. Correlation of these morph...
متن کاملClinical and prognostic significance of lost or decreased PDCD5 expression in human epithelial ovarian carcinomas.
Programmed cell death 5 (PDCD5) is a novel apoptosis-promoting protein. Although the decreased expression of PDCD5 has been recently found in a few types of human tumors, the status and significance of PDCD5 in ovarian cancer has not been evaluated. In the present study, we detected PDCD5 expression in 20 normal human ovaries and 26 serous cystadenomas and 41 serous cystadenocarcinomas by RT-PC...
متن کاملKeratin 5 overexpression is associated with serous ovarian cancer recurrence and chemotherapy resistance
This study investigated the clinical significance of keratin 5 and 6 expression in serous ovarian cancer progression and chemotherapy resistance. KRT5 and KRT6 (KRT6A, KRT6B & KRT6C) gene expression was assessed in publically available serous ovarian cancer data sets, ovarian cancer cell lines and primary serous ovarian cancer cells. Monoclonal antibodies which detect both K5/6 or only K5 were ...
متن کاملOutcome of interval debulking in advanced ovarian cancer patients.
Interval debulking and neoadjuvant chemotherapy have been used in management of advanced epithelial ovarian cancer for many years in order to achieve optimal residual disease and reduce surgical morbidity. The present study was conducted to evaluate the outcomes of advanced ovarian cancer patients treated with these two approaches prior to cytoreductive surgery in Chiang Mai University Hospital...
متن کاملPrognostic Values of Estrogen and Progesterone Expression Receptors in Ovarian Papillary Serous Carcinoma
Background and Objectives: Presence of steroid hormone receptors (estrogen and progesterone) in the tumor tissues of various organs correlates with response to therapy and prognosis. Since their role in ovarian cancer is still controversial, in this study we investigated the expression and prognostic value of the estrogen receptor (ER) and progesterone receptors (PR) in ovarian papillary ser...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2017